server defacing?

it looks like i lefta security hole open and a few sites of mine got defaced. What is the best way to fix this and get everything back to normal??? drop me an e-mail please brendan@puder.com its pretty urgent I picked it uyp before my clients did and i wnat it resolved before 9am tommorow so they will be none the wiser.

Thanks in advance

-puder

 

 

 

 

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