optimizing apache

Hi,

I need technical information how to optimize apache for very heavy duty web server.

Here is the web server characteristic :

- it should serve a lot of users simultaneously.
- clients will upload files to that web server very often (file size is about 200K - 500K).
- it will use MySQL quite a lot.

Please if anyone can give me some pointer of good resources / documents.

Thanks.

 

 

 

 

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