When to HDPARM

I recently learned about hdparm and tuning my hard drive's performance - but I don't know when to run the command. On my RH ES 3.0 box I currently have in rc.local:
Code: 
hdparm -X34 -d1 -u1 -m16 -c3 /dev/hda
but I don't know where to put that on my debian box for when it boots.

Also I know that code works on my Celeron 2.4 box from SM, but do you think my old Dell Dimension XPS D333 can handle that same code on its HDD? I have some wierd errors about waiting for DMA.

 

 

 

 

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