Loopback Network?

On a Windows2003 server, should the DNS of the loopback network be the same as that of the other "Local Area Connection", or can they be different?

This is because I was able to ping the IPs in my loopback until somebody who tried to help me with something else changed a setting for the loopback, which prevented me from doing so now. Besides DNS for Loopback's NIC, can there be other possibilities which prevents me from pinging the IPs?

Thanks.

 

 

 

 

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