500 Internal Error on everything

As it stands now, I've got 2 domains on my server and neither one of them allow browser access to any subdirectories off the main site. I've played with changing the permissions and the ownership to a variety of different settings. This is a FC3 server running cPanel. I'm at a loss here... 500 Internal Error on everything

Can anyone offer any suggestions on what the problem might be?

 

 

 

 

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