apf/iptables problem

We are using apf on one of our servers and multiple times a day pop3 generates errors when trying to connect to get mail
Unable to connect to the server. (Account: 'email@domain.com', POP3 Server: 'domain.com', Error number: 0x800cc0e).

When doing apf -r it connects fine with all accounts after that is been run but then randomly it occurs later in the day. Any thoughts on this/anyone encoutered something similar?

 

 

 

 

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