Running Apache, MySQL, PHP on a Windows in production (hardening system question)

I want to know if there is anyone running these services on a Windows box in production without any issues? I am not necessary running multiple web sites as it's only for one client, however I am concern how reliable Windows 2003 is when it comes to running a dedicated environment with PHP, Apache, and mySQL.

What security measures do you use to harden the system? I also plan on installing a POP3 service on it too for handling email. Is there any reason why I should shun away from using Windows as a platform and stick to something like Redhat Enterprise Server instead?

 

 

 

 

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