Can a mysql/linux backend work with a .net web application?

I was wondering if people have had success using .net and windows for the web tier and using mysql/linux for the database tier?

Given there's a ado.net driver for mysql it should work, but it also sounds risky.

The app is written in .net so there's no other option. But I would I like to save some money on the backend, if possible.

 

 

 

 

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