deleting mail dir files

Hi, i have a simple question, i don't know alot about qmail, im trying to learn. I noticed that /home/vpopmail was taking up quiet some space. I was wondering is it ok for me to delete the files in these dirs?
/home/vpopmail/domains/mydomain.com/postmaster/Maildir/new
/home/vpopmail/domains/funnyjokes.com/postmaster/Maildir/new
one dir is consuming 1 gig, another is 846mb. File names are typically:1001988969.7434.linux1548.dn.net,S=88309

 

 

 

 

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